Eliquis (apixaban) is a prescription medication that treats and prevents certain blood clots. The typical Eliquis dosage in adults is 2.5 mg to 5 mg by mouth twice daily. But your dosage and length of treatment can vary depending on your health condition or situation. There are ways to save on Eliquis.. ESRD maintained on hemodialysis: 5 mg BID; decrease dose to 2.5 mg BID if 1 additional characteristic of age ≥80 years or weight ≤60 kg is present; Postoperative Prophylaxis of DVT/PE. Indicated following hip or knee replacement surgery. Initial: Give 2.5 mg PO 12-24 hr after surgery. Duration of therapy (hip replacement): 2.5 mg PO BID for.

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Eliquis is a brand (trade) name for apixaban which may be given to reduce the risk of blood clots. Eliquis (apixaban) works by selectively inhibiting (blocking) the effects of factor Xa (FXa), an enzyme that plays a key role in the formation of substances that cause blood clotting. Through its action on FXa, apixaban makes blood less likely to.. It is available as tablets (2.5 mg, 5 mg). For patients who have had a hip or knee replacement, treatment with Eliquis should be started 12 to 24 hours after the operation. The recommended dose is one 2.5 mg tablet taken by mouth twice a day, usually for over one month (32 to 38 days) after a hip replacement or for 10 to 14 days after a knee.